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American Chestnut Transgenic Services

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Chestnuts have played an important role in intelligent human cultures worldwide for thousands of years. Chestnuts are an important source of carbohydrates for people in their daily lives. As a global industry, the chestnut industry plays a vital role in the development of the worldwide food industry. Due to the disappearance of the American chestnut, the temperate region of the United States became the only suitable growing region in the world without a chestnut industry. The American chestnut has become an urgent need for the chestnut industry.

Lifeasible focuses on the critical issues facing the American chestnut and is committed to providing a reliable solution for the recovery of the American chestnut, restoring the American chestnut, and creating a truly sustainable food system.

Importance of the American Chestnut

The American chestnut was once a keystone species within its natural range in the United States and Canada. The American chestnut is a fast-growing, long-lived tree that produces large quantities of nuts for human and wildlife consumption. It is also valuable timber and an important source of habitat for wildlife.

Problems Facing the American Chestnut

More than a century ago, an invasive fungal pathogen called Cryphonectria parasitica was introduced to the United States from Asia. Over the next 50 years, the disease spread throughout the natural range of chestnut trees in the Americas, resulting in the death of approximately 90% of chestnut species. Surviving chestnut trees were reduced from key canopy species to insignificant understory trees that produced few viable nuts, resulting in the functional extinction of the American chestnut.

Explore Our Services of Chestnut Transgenic

American chestnut genetic engineering

We are constantly optimizing our American chestnut transgenic protocols. To date, we have tested dozens of transgenes and generated hundreds of transgenic events in American chestnut by combining them with various promoters. We are also developing other transgenic events by using different promoters and transgenic combinations to try to protect chestnut trees from other chestnut pathogens.

For example, we have found several advantages in conferring blight resistance by oxalate oxidase, effectively protecting American chestnut trees from oxalic acid produced by C. parasitica. Single-copy gene expression above a threshold level provides blight resistance similar to that of the Chinese chestnut control, so it could be used to rescue the existing genetic diversity and local adaptation in the remaining remnant populations of American chestnut.

Our genetic engineering services simplify the process of restoring genetic diversity in American chestnut restoration processes and demonstrate increased safety and efficacy against pathogens that invade American chestnut. Using genetic engineering techniques, we have developed blight-resistant trees while avoiding problems such as male sterility in chestnut cross-breeding.

Why Choose Us?

  • We provide various molecular biology services, including gene cloning, genotyping, gene expression analysis, and real-time PCR.
  • We can provide optimal solutions according to the specific research objectives or requirements of various experiments, and can provide technical support for gene manipulation and analysis in American chestnut genetic engineering research.
  • We have highly sensitive sequencing methods integrating nucleic acid extraction, sequencing, bioinformatics analysis, and reporting.

Lifeasibl focuses on the serious problems facing American chestnut development and is committed to providing hope for American chestnut recovery through genetic engineering-related technologies. If you are interested in us, please feel free to contact us.

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