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- Chestnut Genetic Modification Service
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Chestnut Disease-Resistant Service
INQUIRYChestnut is an important cash crop, and diseases, including chestnut blight, anthracnose, and internal rot, seriously threaten and constrain the development of the global chestnut industry. Among them, chestnut blight has led to the near extinction of chestnut trees in the United States. Traditional means of control rely on chemical pesticides, but problems include increased drug resistance and environmental pollution. At the same time, chestnut disease-resistant germplasm resources are scarce, and the conventional breeding cycle is as long as 10-15 years, which makes it challenging to meet the industrial demand. Therefore, biotechnology urgently needs to bring new hope for chestnut disease resistance breeding research.
Lifeasible is an advanced agricultural biotechnology company with many years of research and service experience in chestnut disease research. We have established a comprehensive biotechnology platform and are committed to providing reliable solutions for the prevention and control of major chestnut diseases and the breeding of disease-resistant varieties to promote the healthy development of the chestnut industry.
What We Can Offer?
We provide biotechnology support services related to chestnut disease research, including chestnut blight, internal rot, and many other serious diseases of the chestnut. The specific services are listed below. In addition, we are also expanding our research on disease-resistant breeding of other chestnut diseases. If you have any related research needs, please contact us, our expert technical team will be happy to serve you.
- Chestnut Blight-Resistant Breeding
- Chestnut Yellow Crinkle Disease-Resistant Breeding
- Chestnut Ink Disease-Resistant Breeding
- Chestnut Internal Rot Disease-Resistant Breeding
- Chestnut Anthracnose-Resistant Breeding
- American Chestnut Transgenic Services
Explore Our Chestnut Disease-Resistant Service
Molecular marker-assisted selection (MAS)
- Development of SNP marker microarrays. Based on whole genome resequencing data, we use it to screen molecular markers related to anthracnose and internal rot resistance, to realize seedling resistance phenotype prediction, and to shorten the breeding cycle.
- Multi-gene polymerization breeding. We use marker-assisted backcrossing technology to polymerize disease and virus resistance genes to create broad-spectrum disease-resistant germplasm.
High-throughput disease resistance gene mining
- Combined transcriptome and metabolome analysis. We have analyzed the regulatory network of chestnut in response to pathogen infestation and identified the key genes for phenolic synthesis to guide the improvement of disease resistance through multi-omics analysis.
Functional validation of disease-resistant germplasm
- Pathogen interaction simulation system. Assessing changes in the pathogenicity of gene-edited strains using our specific model. In addition, we use an artificial intelligence system for automated quantitative analysis to achieve several resistance indicators such as lesion area and spore density.
Precision editing of disease resistance genes
- Gene knockout. We utilize advanced gene editing technology to achieve targeted knockout of disease-sensitive genes, such as those related to the pathogenicity of the chestnut epidemic bacterium, to enhance plant resistance.
- Disease-resistant gene introduction. We introduced exogenous disease resistance genes into the chestnut genome through the Agrobacterium-mediated method to enhance the disease resistance of chestnut.
Highlight Our Advanced Technology Platform
| Gene editing innovation platform | Equipped with an advanced gene editing system, especially suitable for editing disease-resistant gene regions with high GC content in chestnut. |
| Multi-omics integrated analysis platform | Based on high-resolution multi-omics profiling, spatio-temporal genomics technology, and cross-modal data fusion algorithms, our integrated multi-omics analysis platform establishes a comprehensive analytical workflow covering data acquisition, processing, and biological interpretation. |
| Molecular detection technology platform | Our molecular detection technology platform can quickly and accurately identify the causative agent of chestnut diseases. |
Why Choose Us?
- Multi-omics integration platform. We unite genomic, phenomic, and microbiomic data to pinpoint resistance regulatory modules.
- Gene editing technology system. We constantly optimize expression vectors and efficient transformation solutions, greatly improving editing efficiency.
- AI-driven design. We use machine learning algorithms to predict disease resistance gene-microbe-environment interaction networks and optimize breeding programs.
- Powerful database. We have a powerful chestnut disease database, covering genomic data of dozens of pathogenic bacteria and resistance phenotypes of thousands of germplasm resources, which supports customized breeding programs.
Relying on an advanced technology platform and a strong technical team of experts, Lifeasible aims to provide high-quality technical support for chestnut disease resistance breeding. If you are interested in us, please feel free to contact us.
※ For research or industrial use.
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